Studies on Enantioselective Addition of Chiral Titanium Reagents to Aromatic Aldehydes

DOI: 10.1055/s-1989-27227

Source and publish data:

Synthesis p. 291 - 292 (1989)

Update date:2022-07-30

Topics:

Authors:

Wang, Ji-Tao

Fan, Xiuju

Feng, Xiao

Qian, Yi-Min

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Article abstract of DOI:10.1055/s-1989-27227

A series of substituted chiral benzhydrols were synthesized by reaction of aromatic aldehydes with the chiral intermediates formed from chiral titanates and arylmagnesium halides.The effect of substituents on the enantioselectivity of the reaction is studied.The reactions are carried out with two different chiral intermediates using two different procedures.

Full text of DOI:10.1055/s-1989-27227

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