Tetrahedron p. 11781 - 11790 (1997)
Update date:2022-07-29
Topics:
Jones, Raymond C. F.
Patel, Pravin
Hirst, Simon C.
Turner, Ian
1-Benzyl-2-(ethoxycarbonyllmethylene)-2,3,4,5-tetrahydroimidazole undergoes preferred C-alkylation with halogenonakanes, dihalogenoalkanes and epoxides: subsequent removal of of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazo[1,2-a]pyridines via C,N-dialkylation.
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