Alkylation of an imidazolidine enaminoester: A new sequence for the c(α)-alkylation of 4,5-dihydroimidazoles

DOI: 10.1016/S0040-4020(97)00752-7

Source and publish data:

Tetrahedron p. 11781 - 11790 (1997)

Update date:2022-07-29

Topics:

Authors:

Jones, Raymond C. F.

Patel, Pravin

Hirst, Simon C.

Turner, Ian

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00752-7

1-Benzyl-2-(ethoxycarbonyllmethylene)-2,3,4,5-tetrahydroimidazole undergoes preferred C-alkylation with halogenonakanes, dihalogenoalkanes and epoxides: subsequent removal of of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazo[1,2-a]pyridines via C,N-dialkylation.

Full text of DOI:10.1016/S0040-4020(97)00752-7

Products guided by the article

Product name:ethyl 1-(1-benzyl-4,5-dihydroimidazol-2-yl)cyclopentanecarboxylate

Cas No:134432-15-8

R&D Labs maybe for 134432-15-8

Hopechem Co., Ltd.

Contact:+86-20-38011066

Address:3510, Diwang Commercial Center, 5002 Shennan Rd, Shenzhen, P.R.China
Changsha Huajing Powdery Material Technological Co., Ltd.

Contact:86-731-88879686

Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Shanghai Yurui Biotechnology(Anyang) Pharmaceutical Co., Ltd

Contact:+86-0372-3662335 +86-0372-3661988

Address:hanling industrial park anyang
Taizhou volsen chemical Co., Ltd

website:http://www.volsenchem.com

Contact:+86-576-88869393

Address:Jiaojiang District, Taizhou, Zhejiang, China.
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China

Relevant to this article

Doi:10.1246/bcsj.41.2211
(1968)
Synthesis of phenazine-tethered arabino and xylofuranosyl oligonucleotide conjugates: The thermal stability and fluorescence properties of their duplexes (DNA-DNA and DNA-RNA) and triplexes

Doi:10.1016/S0040-4020(98)00457-8
(1998)
Vicinal bromostannanes as novel building blocks for the preparation of di- and trisubstituted imidazoles

Doi:10.1016/S0040-4039(98)01056-9
(1998)
A preparation of protected 2-deoxy-2-hydroxymethyl-D-mannose and -D- glucose derivatives not involving organometallic reagents

Doi:10.1016/S0008-6215(98)00080-9
(1998)
Synthesis of the first 2',6 bridged penams

Doi:10.1021/ja980195z
(1998)
An aldol-based approach to the asymmetric synthesis of L-callipeltose, the deoxyamino sugar of L-callipeltoside A.

Doi:10.1021/ol016416e
(2001)

Article Doi