Magnetic Resonance in Chemistry p. 468 - 475 (1991)
Update date:2022-08-03
Topics:
Barraclough, Paul
Firmin, David
Lindon, John C.
Nobbs, Malcolm S.
Sanderson, Paul N.
et al.
The pKa values of six sulmazole analogues were measured spectrophotometrically.The major protonation sites for most of these bridgehead nitrogen heterocycles were determined by 1H and 13C NMR methods.The arylsubstituted imidazo<1,2-a>pyrimidine (4), 8-methoxyimidazo<1,2-a>pyrazine (6), imidazo<1,2-b>pyridazine (9) and imidazo<1,2-b><1,2,4>triazine (11) undergo protonation at the imidazo nitrogen.The imidazo<1,2-a>pyrazine (5) protonates mainly at N-7.In some cases differences in basicity properties between these aryl analogues and the bridgehead heterocycles have been observed.KEY WORDS Polyazaindolizines Protonation 13C NMR 1H NMR pK values
View MoreShenzhen Feiming Science and Technology Co,. Ltd
Contact:+86-755-85232577
Address:#B2309, Fenglin International Center ,Jixiang Road, Longcheng street, LongGang District, Shenzhen city, Guangdong province, China.
Hangzhou yi lu biont technology Co., LTD
Contact:+86-571-88152630
Address:Hangzhoushi HuafengRoad Yicheng3Building1001room.
Xi'an Unique Electronic and Chemical Co., Ltd.
Contact:+86-029-88238008
Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Shandong united-rising pharmaceutical cooperation.,ltd.
Contact:008653187965009
Address:171No., Jing5 Road, Shizhong District, Jinan, China
Contact:+86-512-56795332
Address:No227 Shuanglong Rd, Fenghuang, Zhangjiagang
Doi:10.1002/ejoc.200500390
(2005)Doi:10.1021/jo00016a014
(1991)Doi:10.1007/BF00476755
(1991)Doi:10.1007/BF00902579
(1966)Doi:10.1002/cmdc.201100288
(2011)Doi:10.1246/cl.2011.1009
(2011)
