Applications of Crotyldiisopinocampheylboranes in Synthesis: The Total Synthesis of Nikkomycin B

Article abstract of DOI:10.1021/jo00016a014

(-)-(E)-Crotyldiisopinocampheylborane was employed in a highly diastereoselective and enantioselective synthesis of the γ-hydroxy-β-methyl-α-aminobutanoic acid moiety of nikkomycin B.A protected derivative of this N-terminal amino acid residue was condens