Applications of Crotyldiisopinocampheylboranes in Synthesis: The Total Synthesis of Nikkomycin B

DOI: 10.1021/jo00016a014

Source and publish data:

Journal of Organic Chemistry p. 4875 - 4884 (1991)

Update date:2022-08-03

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Authors:

Barrett, Anthony G. M.

Lebold, Suzanne A.

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Article abstract of DOI:10.1021/jo00016a014

(-)-(E)-Crotyldiisopinocampheylborane was employed in a highly diastereoselective and enantioselective synthesis of the γ-hydroxy-β-methyl-α-aminobutanoic acid moiety of nikkomycin B.A protected derivative of this N-terminal amino acid residue was condens

Full text of DOI:10.1021/jo00016a014

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