Reaction of Quinazoline-2,4(1H,3H)-dione with N-Substituted Cyclic Amines in Combination with Phosphoryl Trichloride

DOI: 10.1039/P19910001279

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1279 - 1282 (1991)

Update date:2022-07-30

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Authors:

Yoshida, Kenji

Tanaka, Takashi

Ohtaka, Hiroshi

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Article abstract of DOI:10.1039/P19910001279

The reaction of quinazoline-2,4(1H,3H)-dione with N-allyl, N-benzyl and N-methyl cyclic amines in combination with phosphoryl trichloride in the presence of tripropylamine in 1,4-dioxane afforded 4-chloro-2-(cycloalkylamino)quinazolines.In the case of N-s

Full text of DOI:10.1039/P19910001279

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