Synthesis of 2-trifluoromethylpyrazolo[5,1-a]isoquinolines via silver triflate-catalyzed or electrophile-mediated one-pot tandem reaction

Article abstract of DOI:10.3762/bjoc.10.238

An efficient one-pot tandem cyclization/[3 + 2] cycloaddition reaction of N '-(2-alkynylbenzylidene)hydrazides with ethyl 4,4,4- trifluorobut-2-ynoate under silver triflate-catalyzed or electrophile-mediated conditions is described. Various trifluoromethy