Solid-phase synthesis of 2′-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines

DOI: 10.1016/j.bmc.2011.11.042

Source and publish data:

Bioorganic and Medicinal Chemistry p. 25 - 33 (2012)

Update date:2022-07-30

Topics:

Authors:

Neves, Marta Perro

Cravo, Sara

Lima, Raquel T.

Vasconcelos, M. Helena

Nascimento, M. S?o José

Silva, Artur M.S.

Pinto, Madalena

Cidade, Honorina

Corrêa, Arlene G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmc.2011.11.042

Thirty-one 2′-hydroxychalcones were prepared via solid-phase synthesis by base-catalyzed aldol condensation of substituted 2′-hydroxyacetophenones and benzaldehydes. Chalcones were tested for their growth inhibitory activity in three human tumor cell line

Full text of DOI:10.1016/j.bmc.2011.11.042

Products guided by the article

Product name:4-chloro-2',4'-dihydroxy-3'-methylchalcone

Cas No:1355027-37-0

R&D Labs maybe for 1355027-37-0

Nanjing Qirui Material Co., Ltd.

Contact:+86-25-52320053

Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
TC CHEMICALS CO.,LTD

Contact:0550-7041128 0550-7090578

Address:Wangdian Street,Xinjie Town
ZhangJiaGang YaRui Chemical Co.,Ltd.

Contact:0512-58360968

Address:China JiangSu Province Zhang Jia Gang City YangShe Oriental Plaza Building 10 B307
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
Shanghai doly chemical Co.,Ltd

Contact:+86-21-34716221

Address:No.328,WuHe Roard,MinHang,ShangHai China

Relevant to this article

Synthesis and in vitro evaluation of 2-[¹¹C]methoxyestradiol-3, 17β-O,O-bissulfamate for in vivo studies of angiogenesis

Doi:10.1002/jlcr.1930
(2011)
Synthesis of hydroxyl-containing oxindoles and 3,4-dihydroquinolin-2-ones through oxone-mediated cascade arylhydroxylation of activated alkenes

Doi:10.1039/d0gc02205e
(2020)
Synthesis, crystal structure and ab initio studies of 5-Phenylamino-3- phenylimino-3H[1, 2]dithiole-4-carboxylic acid ethyl ester

Doi:10.1007/s10870-011-0196-2
(2011)
Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E₂ synthase-1

Doi:10.1016/j.ejmech.2011.12.009
(2012)
Synthesis and fluorescence properties of Tb(III) complex with a novel β-diketone ligand as well as spectroscopic studies on the interaction between Tb(III) complex and bovine serum albumin

Doi:10.1016/j.molstruc.2011.11.041
(2012)
Mass spectrometry and quantum chemical studies of the reaction of divinyl telluride with secondary phosphine sulfides: Synthesis of adducts

Doi:10.1016/j.jorganchem.2013.07.050
(2013)

Article Doi