Synthesis and in vitro evaluation of 2-[11C]methoxyestradiol-3, 17β-O,O-bissulfamate for in vivo studies of angiogenesis

DOI: 10.1002/jlcr.1930

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 783 - 787 (2011)

Update date:2022-07-30

Topics:

Authors:

Kang, Choong Mo

Choe, Yearn Seong

Jung, Kyung-Ho

Choi, Joon Young

Lee, Kyung-Han

Kim, Byung-Tae

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Article abstract of DOI:10.1002/jlcr.1930

In the present study, 2-methoxyestradiol-3,17β-O,O-bissulfamate (1), a known angiogenesis inhibitor, was prepared in a radiolabeled form by ¹¹C-methylation of 2-hydroxyestradiol-3,17β-O,O-bis(N-trityl) sulfamate (6) followed by detritylation. S

Full text of DOI:10.1002/jlcr.1930

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