Diene-dienophile hydrogen-bonding control of diels-alder reactions with dienes bearing a remote stereogenic center. Amplification of the receptor nature of dienes by conformational tuning leading to high diastereofacial discrimination

Article abstract of DOI:10.1021/ja00020a026

The Diels-Alder reactions of 1-(O-methylmandeloxy)butadiene and its analogues, bearing a remote stereogenic center, have been studied to elucidate the stereoselective control elements. Several model dienes (5a-5f) have been designed to enhance the facial