Fluoromethylated and hydroxymethylated derivatives of N-methyl-D-aspartate receptor antagonist 1-[1-(2-thienyl)cyclohexyl]piperidine

DOI: 10.1248/cpb.39.1581

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1581 - 1584 (1991)

Update date:2022-07-30

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Authors:

Tsukiyama

Hashimoto

Katayama

Nishikawa

Tobe Tobe

Maeda Maeda

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Article abstract of DOI:10.1248/cpb.39.1581

Derivatives with fluoromethyl and hydroxymethyl groups on the cyclohexyl ring of 1-[1-(-2-thienyl)cyclohexyl]piperidine (TCP), a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor, were tested in a radioligand binding assay to evaluate thei

Full text of DOI:10.1248/cpb.39.1581

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