(Aminoalkyl)carbamates of Forskolin: Intermediates for the Synthesis of Functionalized Derivatives of Forskolin with Different Specificities for Adenylyl Cyclase and the Glucose Transporter

DOI: 10.1021/jm00115a009

Source and publish data:

Journal of Medicinal Chemistry p. 3204 - 3212 (1991)

Update date:2022-07-29

Topics:

Authors:

Robbins, Joan D.

Laurenza, Antonio

Kosley, Raymond W.

O'Malley, Gerard J.

Spahl, Bettina

Seamon, Kenneth B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00115a009

(Aminoalkyl)carbamates of forskolin were synthesized at the 6- and 7-hydroxyl positions of forskolin with the length of the alkyl chain varying from ethyl to heptyl.Two of these derivatives, 7-<<(2-aminoethyl)amino>carbonyl>-7-desacetylforskolin (2) and 6

Full text of DOI:10.1021/jm00115a009

Products guided by the article

Product name:{4-[3-(4-Hydroxy-phenyl)-propionylamino]-butyl}-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-6-yl ester

Cas No:136327-90-7

R&D Labs maybe for 136327-90-7

Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
N&R INDUSTRIES,INC

Contact:Tel:+86-29-88764861 Fax:+86-29-88764861

Address:Rm#2107, Block A, Epin Meidao Building, Gaoxin Rd, Hi-Tech Zone, Xi’an, China
LIANYUNGANG YC FINE CHEMICAL CO., LTD

Contact:+86-518-858 99188

Address:Shangdong Modern Bldg, South Greenpark Road, Lianyungang, Jiangsu Pro. China

Relevant to this article

Improvement of estradiol esters monitoring in bovine hair by dansylation and liquid chromatography/tandem mass spectrometry analysis in multiple reaction monitoring and precursor ion scan modes

Doi:10.1002/rcm.6160
(2012)
A facile preparation of 3-alkylindoles via Wittig reaction of 1-acetylindol-3(2H)-ones with stabilized phosphonium ylides

Doi:10.1055/s-1991-26550
(1991)
N-alkylation using sodium triacetoxyborohydride with carboxylic acids as alkyl sources

Doi:10.1248/cpb.c17-00716
(2018)
Syntheses and electrochemical properties of novel aminopyrimidinone derivatives as a new class of abasic-site binders

Doi:10.1007/s11164-012-0641-7
(2013)
Regiospecific Palladium-Catalyzed Cycloaddition of Aziridines and Carbodiimides

Doi:10.1021/jo00027a030
(1992)
Synthesis, structure and reactivity of iridium hydrido fluorido complexes

Doi:10.1002/ejic.201100917
(2012)

Article Doi