A bireactant, irreversible, active-site-directed inhibitor of β-D-galactosidase (Escherichia coli). Synthesis and properties of (1/2,5,6)-2-(3-azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol

DOI: 10.1016/S0008-6215(00)90528-7

Source and publish data:

Carbohydrate Research p. 35 - 41 (1991)

Update date:2022-08-04

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Authors:

Huber Huber

Lehmann Lehmann

Ziser Ziser

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Article abstract of DOI:10.1016/S0008-6215(00)90528-7

(1/2,5,6)-2-(3-Azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol (1) was synthesized and was found to irreversibly inactivate β-D-galactosidase (Escherichia coli). The inactivation was prevented by the presence of isopropyl 1-thio-β-D-galactopyranoside (IPTG). Th

Full text of DOI:10.1016/S0008-6215(00)90528-7

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