Synthetic Communications p. 1724 - 1730 (2012)
Update date:2022-07-30
Topics:
Demizu, Yosuke
Sano, Kaichi
Terayama, Naoki
Hakamata, Wataru
Sato, Yukiko
Inoue, Hideshi
Okuda, Haruhiro
Kurihara, Masaaki
This study demonstrates solid-phase nucleophilic fluorination. Polymer-bound 1-phenoxy-2-sulfonyloxyethane, as a model compound, is converted to a fluorinated compound in a short time. Furthermore, this method is applied to synthesize a precursor of 2-deoxy-2-fluoro-D-glucose by solid-phase synthesis using a microwave oven. Copyright Taylor & Francis Group, LLC.
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(2012)