Tetrahedron Letters p. 3859 - 3862 (1991)
Update date:2022-08-04
Topics:
Grigg, Ronald
Teasdale, Andrew
Sridharan, Visuvanathar
A Pd(0)/R3Sn)2 (R=Me or n-Bu) catalyst system effects intramolecular aryl-aryl, benzyl-aryl, benzyl-benzyl coupling of aryl and benzyl halides in good yield. Polycyclisations can be achieved by relaying the coupling via an alkene or alkyne "linker". The methodology is exemplified by a short synthesis of hippadine.
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Doi:10.1002/anie.201105735
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(2012)Doi:10.1021/acscatal.1c02144
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(1991)
