Antitumor agents. II: Regio- and stereospecific syntheses of 1-β-alkyl-1-desoxypodophyllotoxin derivatives and biological activity

DOI: 10.1248/cpb.41.907

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 907 - 912 (1993)

Update date:2022-08-04

Topics:

Authors:

Terada Terada

Fujimoto

Nomura Nomura

Yamashita

Wierzba Wierzba

Kobunai Kobunai

Takeda Takeda

Minami Minami

Yoshida Yoshida

Yamaguchi

Yamada Yamada

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.41.907

1-β-Alkyl derivatives of 1-desoxypodophyllotoxin were synthesized, and their cytotoxicity and inhibitory effects on DNA topoisomerase II (Topo-II) and tubulin polymerization were examined. The reaction of epipodophyllotoxin derivatives (1a-c) with trimeth

Full text of DOI:10.1248/cpb.41.907

NII-Electronic Library Service

Products guided by the article

Product name:1-β-propyl-1-desoxypodophyllotoxin

Cas No:136755-67-4

R&D Labs maybe for 136755-67-4

SHENZHEN PENGCHENG REDSTAR INDUSTRY CO.,LTD

Contact:+86-755-82412922

Address:Room 8066, East Block, Square City, Jiabin Road, Luohu District
Liaoning Yufeng Chemical Co.,Ltd.

Contact:86-0419-3418888

Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
GBXF SILICONES CO.,LTD

website:http://www.gbxfsilicones.com/

Contact:86-25-68900673

Address:He Country Provincial Fine Chemical Industrial Park of Chaohu city,Anhui province,China
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
Baoding City Light Industry And Textiles Imp.& Exp. Corp. Chemical Department.

Contact:86-312-3262436

Address:NO.658 CHAOYANG SOUTH STREET,BAODING CITY HEBEI CHINA

Relevant to this article

Synthesis of precursors for medium-ring aromatic lactones

Doi:10.1055/s-2005-865364
(2005)
Palladacycles derived from arylphosphinamides for mild Suzuki-Miyaura cross-couplings

Doi:10.1039/c5ra12742d
(2015)
3-Hydroxydihydrobenzofuran glucosides from Gnaphalium polycaulon

Doi:10.1248/cpb.59.1160
(2011)
Synthesis and controlled self-assembly of covalently linked hexa- peri -hexabenzocoronene/perylene diimide dyads as models to study fundamental energy and electron transfer processes

Doi:10.1021/ja211504a
(2012)
Radiolabeled γ-AApeptides: A new class of tracers for positron emission tomography

Doi:10.1039/c2cc33620k
(2012)
Highly stereoselective glycosylation by conformational assistance of glycosyl donor

Doi:10.1016/0040-4039(91)80435-9
(1991)

Article Doi