Bioorganic and Medicinal Chemistry Letters p. 6286 - 6291 (2012)
Update date:2022-08-03
Topics:
Banerjee, Abhisek
Patil, Sandip
Pawar, Mahesh Y.
Gullapalli, Srinivas
Gupta, Praveen K.
Gandhi, Maulik N.
Bhateja, Deepak K.
Bajpai, Malini
Sangana, Ramachandra Rao
Gudi, Girish S.
Khairatkar-Joshi, Neelima
Gharat, Laxmikant A.
The synthesis and structure-activity relationship studies of a series of compounds from imidazopyridazinone scaffold as PDE7 inhibitors are disclosed. Potent analogs such as compounds 7 (31 nM), 8 (27 nM), and 9 (12 nM) were identified. The PDE selectivit
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Doi:10.1055/s-0037-1610326
(2018)Doi:10.1021/mp300009u
(2012)Doi:10.1021/jo300562j
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(2020)Doi:10.1039/c2ob25433f
(2012)