Inactivation of calpain by peptidyl fluoromethyl ketones

DOI: 10.1021/jm00080a003

Source and publish data:

Journal of Medicinal Chemistry p. 216 - 220 (1992)

Update date:2022-08-05

Topics:

Authors:

Angliker

Anagli Anagli

Shaw Shaw

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Article abstract of DOI:10.1021/jm00080a003

The syntheses of Z-Leu-Leu-Tyr-CH₂F (1) and Z-Tyr-Ala-CH₂F (3) are described. The ability of Z-Leu-Leu-Tyr-CH₂F (1) and Z-Leu-Tyr-CH₂F (2) to inactivate in vitro calcium-activated proteinase from chicken gizzard

Full text of DOI:10.1021/jm00080a003

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