Alkylation of Aromatic Heterocycles with Oxalic Acid Monoalkyl Esters in the Presence of Trivalent Iodine Compounds

DOI: 10.1246/cl.1991.1691

Source and publish data:

Chemistry Letters p. 1691 - 1694 (1991)

Update date:2022-08-04

Topics:

Authors:

Togo, Hideo

Aoki, Masahiko

Yokoyama, Masataka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1991.1691

Aromatic heterocycles containing nitrogen atoms were easily alkylated with the half esters of oxalic acid, which were prepared from alcohols, in the presence of benzene via radical decarboxylative pathways.This is the first method for the alkylation of aromatic heterocycles with alcohols via the formation of half esters of oxalic acid.

Full text of DOI:10.1246/cl.1991.1691

Products guided by the article

Product name:methyl 2-(1-methylcyclohexyl)isonicotinate

Cas No:137634-67-4

R&D Labs maybe for 137634-67-4

ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
Afine Chemicals Limited

website:http://www.afinechem.com

Contact:+86-571-85134551

Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
Buffett (China) Holding Co.,Ltd

Contact:4006570891

Address:
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
SHAANXI FUJIE PHARMACEUTICAL CO.,LTD

website:http://www.fujiepharm.com

Contact:+86-29-63650906

Address:Yuanqu Yi Road, Qinghe Food Industrial Park, Sanyuan County, Shaanxi Province, China

Relevant to this article

HPLC-assisted automated oligosaccharide synthesis

Doi:10.1021/ol301105y
(2012)
Reactions of Azoarenes with Tributyltin Hydride

Doi:10.1021/jo00028a038
(1992)
Synthesis of 1,3-dienes bearing both electron-donor and acceptor substituents

Doi:10.1016/0040-4039(91)80074-G
(1991)
Enantioselective Total Synthesis of (+)-Monocerin, a Dihydroisocoumarin Derivative with Potent Antimalarial Properties

Doi:10.1021/acs.joc.9b00414
(2019)
Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents

Doi:10.1016/j.bmc.2012.03.064
(2012)
Magnetically separable nano Fe₃O₄ catalyzed direct azidation of allylic and benzylic alcohols followed by copper-catalyzed click reaction

Doi:10.1055/s-0034-1378517
(2014)

Article Doi