Synthesis and Anti-HIV Activity of 4'-Thio-2',3'-dideoxynucleosides

DOI: 10.1021/jm00081a015

Source and publish data:

Journal of Medicinal Chemistry p. 533 - 538 (1992)

Update date:2022-08-02

Topics:

Authors:

Secrist, John A.

Riggs, Robert M.

Tiwari, Kamal N.

Montgomery, John A.

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Article abstract of DOI:10.1021/jm00081a015

A series of 2',3'-dideoxy-4'-thionucleoside analogues of purines and pyrimidines, including 4'-thioddI (17), 4'-thioddC (27), and 4'-thioAZT (34), were synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV).A st

Full text of DOI:10.1021/jm00081a015

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