ASYMMETRIC SYNTHESIS OF TOPOGRAPHICALLY CONSTRAINED AMINO ACIDS: SYNTHESIS OF THE OPTICALLY PURE ISOMERS OF α,β-DIMETHYL-PHENYLALANINE AND α,β-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID

Article abstract of DOI:10.1016/S0040-4039(00)93551-2

All four isomers of α,β-dimethylphenylalanine and α,β-dimethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid have been synthesized in high optical purity for use in the design of topographically constrained peptides.