Antitumor agents. 124. New 4β-substituted aniline derivatives of 6,7-O,O- demethylene-4'-O-demethylpodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II

DOI: 10.1021/jm00083a010

Source and publish data:

Journal of Medicinal Chemistry p. 871 - 877 (1992)

Update date:2022-07-29

Topics:

Authors:

Wang Wang

Chen Chen

Cheng Cheng

Lee Lee

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Article abstract of DOI:10.1021/jm00083a010

A series of 6,7-O,O-demethylene-4'-O-demethyl-4β-(substituted anilino)-4- desoxypodophyllotoxins (18-23), 6,7-O,O-demethylene-6,7-O,O-dimethyl-4'-O- demethyl-4β-(substituted anilino)-4-desoxypodophyllotoxins (28-31), and their corresponding 4'-O-methyl an

Full text of DOI:10.1021/jm00083a010

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