Cycloadducts of Ethene with 2(1H)-Pyrazinones and their conversion into 2,5-Diazabicyclooctane-3,6-diones.

DOI: 10.1016/S0040-4020(01)96214-3

Source and publish data:

Tetrahedron p. 9259 - 9268 (1991)

Update date:2022-08-03

Topics:

Authors:

Loosen, Patrick K.

Tutonda, Mayoka G.

Khorasani, Masoumeh F.

Compernolle, Frans

Hoornaert, Georges J.

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Article abstract of DOI:10.1016/S0040-4020(01)96214-3

Cycloaddition of variously substituted 2(1H)-pyrazinones with ethene and subsequent hydrolysis of the adducts 2 provides a general and efficient route to the title compounds 3.Compound 3m was used as a building block for a structural analogue of gliotoxin

Full text of DOI:10.1016/S0040-4020(01)96214-3

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