Bioorganic and Medicinal Chemistry Letters p. 699 - 704 (1998)
Update date:2022-07-29
Topics:
Yao, Shao
Zutshi, Reena
Chmielewski, Jean
Endothiopeptide inhibitors of HIV-1 protease were synthesized by chemical and enzymatic methods to individually replace each backbone amide bond in 1 with a thioamide-linkage. Interestingly, agent 7, which contains a thioamide-linkage between the P2<
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