Endothiopeptide inhibitors of HIV-1 protease

DOI: 10.1016/S0960-894X(98)00100-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 699 - 704 (1998)

Update date:2022-07-29

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Authors:

Yao, Shao

Zutshi, Reena

Chmielewski, Jean

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Article abstract of DOI:10.1016/S0960-894X(98)00100-0

Endothiopeptide inhibitors of HIV-1 protease were synthesized by chemical and enzymatic methods to individually replace each backbone amide bond in 1 with a thioamide-linkage. Interestingly, agent 7, which contains a thioamide-linkage between the P_2<

Full text of DOI:10.1016/S0960-894X(98)00100-0

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