A new route to 6-substituted 2,3-diaminopyridines

DOI: 10.1016/0040-4039(91)80204-J

Source and publish data:

Tetrahedron Letters p. 6503 - 6506 (1991)

Update date:2022-08-05

Topics:

Authors:

Bussolotti

LaMattina

James James

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Article abstract of DOI:10.1016/0040-4039(91)80204-J

2,3-Diaminopyridine reacts with cyclohexanone to form dihydro-4-azabenzimidazole-2-spirocyclohexane. Reaction of this intermediate with a variety of nucleophiles (e.g., water, phenylmercaptan, ethanol, dimethylamine, and diethylmalonate) in the presence o

Full text of DOI:10.1016/0040-4039(91)80204-J

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