Asymmetric synthesis and determination of the absolute configuration of FK584, an agent for the treatment of overactive detrusor

DOI: 10.1248/cpb.48.1903

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1903 - 1907 (2000)

Update date:2022-09-26

Topics:

Authors:

Take Take

Okumura Okumura

Tsubaki Tsubaki

Taniguchi

Shiokawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.48.1903

FK584[(-)-N-tert-butyl-4,4-diphenyl-2-cyclopentenylamine hydrochloride, (-)-4·HCl], a potential candidate for the treatment of overactive detrusor, was synthesized in a 4-step approach starting with Sharpless oxidation of cyclopentenol 6 (kinetic resoluti

Full text of DOI:10.1248/cpb.48.1903

NII-Electronic Library Service

Products guided by the article

Product name:2-Cyclopenten-1-ol, 4,4-diphenyl-

Cas No:138952-01-9

R&D Labs maybe for 138952-01-9

Shanghai HengXun Pharmaceutical Tech. Co., Ltd.

Contact:86-86-52730756

Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
Reliable Pharma Technology (Shanghai) Co., Ltd.

Contact:0086-21-67676847-8008

Address:Lane 1500, No.68, Xinfei Road, Songjiang District, Shanghai, 201611, P.R.China.
Chengdu ZY Biochemical Technology Co., LTD

Contact:0086-28-88680086

Address:170 Qingpu Road, Shouan Town, Pujiang County
Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China

Relevant to this article

H-Bond assisted mechanoluminescence of borylated aryl amines: Tunable emission and polymorphism

Doi:10.1039/c7tc01676j
(2017)
Cu(N-heterocyclic carbene)chloride: An efficient catalyst for multicomponent click reaction for the synthesis of 1,2,3-triazoles in water at room temperature

Doi:10.1039/c4ra08412h
(2014)
Efficient Synthesis of Optically Active Neolignans Ligraminol D and e

Doi:10.1055/s-0037-1611919
(2019)
Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids

Doi:10.1021/jf2029708
(2011)
A robust and recyclable polyurea-encapsulated copper(I) chloride for one-pot ring-opening/Huisgen cycloaddition/CO₂ capture in water

Doi:10.1039/c6gc01956k
(2016)
Doi:10.1021/jo01349a515
(1966)

Article Doi