Asymmetric synthesis and determination of the absolute configuration of FK584, an agent for the treatment of overactive detrusor

DOI: 10.1248/cpb.48.1903

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1903 - 1907 (2000)

Update date:2022-09-26

Topics:

Authors:

Take Take

Okumura Okumura

Tsubaki Tsubaki

Taniguchi

Shiokawa

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Article abstract of DOI:10.1248/cpb.48.1903

FK584[(-)-N-tert-butyl-4,4-diphenyl-2-cyclopentenylamine hydrochloride, (-)-4·HCl], a potential candidate for the treatment of overactive detrusor, was synthesized in a 4-step approach starting with Sharpless oxidation of cyclopentenol 6 (kinetic resoluti

Full text of DOI:10.1248/cpb.48.1903

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