A novel stereoselective synthesis of (+)-cerulenin and (+)-tetrahydrocerulenin

Article abstract of DOI:10.1016/S0040-4039(00)93599-8

An antibiotic natural (+)-cerulenin and (+)-tetrahydrocerulenin have been synthesized, based on successive alkylation and reduction of chiral cyclic imide with C₂-symmetry derived from D-tartaric acid.