
Tetrahedron Letters p. 1319 - 1322 (1999)
Update date:2022-07-29
Topics:
Nemoto
Ibaragi
Bando
Kido
Shibuya
A highly stereoselective synthesis of an alkenylated malonic diamide starting from a γ,δ-epoxy-α,β-unsaturated carboxamide was accomplished using the masked acyl cyanide (MAC: the protected hydroxymalonitrile) via palladium-catalyzed regio- and stereoselective carbon-carbon bond formation.
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