The synthesis of chiral α,β-unsaturated and aryl oxazolines from ketones and arols via their triflates and Pd-catalyzed CO and amino alcohol coupling

Article abstract of DOI:10.1016/S0040-4039(00)91890-2

An efficient route to the title compounds was achieved using the triflates of ketones and phenols followed by Pd-catalyzed CO insertion in the presence of chiral amino alcohols. Aryl, vinyl bromides and 2-pyridone also served as useful substrates.