Novel 5-Desmethylene Analogues of 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid as Potential Anticancer Agents

DOI: 10.1021/jo00037a047

Source and publish data:

Journal of Organic Chemistry p. 3218 - 3225 (1992)

Update date:2022-08-02

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Authors:

Taylor, Edward C.

Gillespie, Paul

Patel, Mona

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Article abstract of DOI:10.1021/jo00037a047

The synthesis and biological activity of novel 5-desmethylene analogues of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF), a potent antitumor agent presently undergoing clinical trials, are described.These compounds are representative of a new series

Full text of DOI:10.1021/jo00037a047

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