Journal of Organic Chemistry p. 3218 - 3225 (1992)
Update date:2022-08-02
Topics:
Taylor, Edward C.
Gillespie, Paul
Patel, Mona
The synthesis and biological activity of novel 5-desmethylene analogues of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF), a potent antitumor agent presently undergoing clinical trials, are described.These compounds are representative of a new series
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