
Journal of Medicinal Chemistry p. 1782 - 1791 (1992)
Update date:2022-08-03
Topics:
Wolfe, Michael S.
Lee, Younha
Bartlett, William J.
Borcherding, David R.
Borchardt, Ronald T.
The carbocyclic adenosine analogues aristeromycin and neplanocin A both display significant S-adenosyl-L-homocysteine (AdoHcy) hydrolase inhibitory activity and broad-spectrum antiviral effects.Since phosphorylation of the 4'-hydroxymethyl substituent has
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