Reactivity of Malonyl Radicals. Synthesis of Substituted Dihydronaphthalenes by Mn(III) Oxidation of Diethyl α-Benzylmalonate in the Presence of Alkynes

DOI: 10.1021/jo00041a034

Source and publish data:

Journal of Organic Chemistry p. 4250 - 4255 (1992)

Update date:2022-08-04

Topics:

Authors:

Santi, Roberto

Bergamini, Fabrizio

Citterio, Attilio

Sebastiano, Roberto

Nicolini, Marco

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Article abstract of DOI:10.1021/jo00041a034

Oxidation of diethyl α-benzylmalonate (1) by Mn(III) acetate in acetic acid at 70 deg C in the presence of alkynes 2a-j leads to dihydronaphthalene derivatives 3a-j in moderate to good yields.A homolytic mechanism, involving oxidation of 1 to the correspo

Full text of DOI:10.1021/jo00041a034

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