Novel Synthesis of Nitrogen Heterocycles Using Zirconium-Promoted Reductive Coupling. Formal Total Synthesis of Dendrobine

Article abstract of DOI:10.1021/jo00039a001

A novel synthesis of nitrogen heterocycles by means of a zirconium-promoted, intramolecular reductive coupling reaction of an enyne or a diene was developed, and the formal total synthesis of dendrobine from (-)-carvone was achieved by a short sequence of steps.