Novel [1,3]-migration of methyl group in imidazo[4,5-c]quinoline

Article abstract of DOI:10.1016/0040-4039(92)88131-N

In synthetic studies of imidazo[4,5-c]quinolin-4(5H)-one derivatives, which exhibit a potent antiasthmatic activity, an unusual rearrangement was observed, where the methyl group migrates from the N-1 to the N-3 position on the imidazole during the reacti