An unusual twist in the synthesis and hydrolysis of the 23,24-epoxide of 22,23-dihydroavermectinB(1a)

DOI: 10.1016/S0040-4039(00)91712-X

Source and publish data:

Tetrahedron Letters p. 1709 - 1712 (1992)

Update date:2022-08-06

Topics:

Authors:

Shih Shih

Mrozik Mrozik

Holmes Holmes

Arison Arison

Doss Doss

Waksmunski

Fisher Fisher

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)91712-X

Treatment of 4'',5-di-O-tert-butyldimethylsilyl (or phenoxyacetyl)-7-O-trimethylsilyl-avermectin B(2a) (1a,b) with diethylaminosulfur trifluoride (DAST) at 20AC in dichloromethane resulted in net elimination of water to yield 65% of the 23,24-olefin (2a,b

Full text of DOI:10.1016/S0040-4039(00)91712-X

Products guided by the article

Product name:C₆₇H₉₄O₁₉Si

Cas No:141625-69-6

R&D Labs maybe for 141625-69-6

ORCHID CHEMICAL SUPPLIES LTD

website:http://www.orchid-chem.com

Contact:+86-571-85395792

Address:607, North Zhongshan Road, Hangzhou 310000 China
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china
Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China
Nantong Kaixin Pharma Chemical Co.,Ltd.

Contact:86-513-85250786

Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China

Relevant to this article

Enantioselective Cyano-Alkoxycarbonylation of α-Oxoesters Promoted by Br?nsted Acid-Lewis Base Cooperative Catalysts

Doi:10.1021/acs.orglett.5b03093
(2015)
Palladium-catalyzed 1,4-addition of carboxylic acids to butadiene monoxide

Doi:10.1002/adsc.201200059
(2012)
N,N'-Dimethoxy-N,N'-dimethylethanediamide: A useful α-oxo-N-methoxy-N-methylamide and 1,2-diketone synthon

Doi:10.1016/0040-4039(92)88108-H
(1992)
Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)

Doi:10.1016/j.ejmech.2016.06.010
(2016)
Synthesis of polysubstituted naphthalenes by iron-catalyzed [2+2+2] annulation of grignard reagents with alkynes

Doi:10.1055/s-0032-1317077
(2012)
CF₃SO₃H-SiO₂ as catalyst for Ferrier rearrangement: An efficient procedure for the synthesis of pseudoglycosides

Doi:10.1016/j.tet.2012.11.019
(2013)

Article Doi