A novel and expeditious route to A-81988: An angiotensin II receptor antagonist

Article abstract of DOI:10.1080/00397919608003705

A novel and efficient synthesis of A-81988, an angiotensin II receptor antagonist, is described. The key step utilizes a palladium-catalyzed biaryl coupling between a phenylboronic acid derivative and N-trityl-5-(2-bromophenyl)tetrazole.

Full text of DOI:10.1080/00397919608003705

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Synthetic Communications:
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A Novel and Expeditious
Route to A-81988: An
Angiotensin II Receptor
Antagonist
Francis A. J. Kerdesky a & Thomas J. Sowin a
a Process Research, Department 45L,
Pharmaceutical Products Division , Abbott
Laboratories , North Chicago, Illinois, 6004
Published online: 21 Aug 2006.
To cite this article: Francis A. J. Kerdesky & Thomas J. Sowin (1996) A Novel and
Expeditious Route to A-81988: An Angiotensin II Receptor Antagonist, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:5, 1007-1013, DOI: 10.1080/00397919608003705
To link to this article: http://dx.doi.org/10.1080/00397919608003705
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