Attachment of vitamin E derivatives to oligonucleotides during solid-phase synthesis

Article abstract of DOI:10.1016/S0040-4039(00)79068-X

Compounds have been synthesized which allow the attachment of Vitamin E to the 5'-, and 3'-ends of oligonucleotides, and the attachment of a Vitamin E moiety on an octamethylene spacer to the 5'-end, all during solid-phase synthesis. The effects on cellul