Tetrahedron Letters p. 2249 - 2252 (1992)
Update date:2022-07-29
Topics: Asymmetric synthesis Catalyst Chemoenzymatic synthesis Chemical Synthesis Enzymatic Reaction Deazapurine Chiral compound
Chen, Xing
Siddiqi, Suhaib M.
Schneller, Stewart W.
The enantioselective synthesis of (-)-(1R,2S,3S)-2-amino-7-<2,3-bis(hydroxymethyl)cyclobutyl>pyrrolo<2,3-d>pyrimidin-4(3H)-one (5) as the 7-deaza analogue of carbocyclic oxetanocin G is described in 13 steps from trans-3,3-diethoxy-1,2-bis(hydroxymethyl)c
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