Ring Opening of the Epoxide Moiety of (2S,3S,4S)-4-Amino-2,3-epoxy-1-alkanol and Its Derivatives: A Key Role of Ti(O-i-Pr)4 as a Mild Catalyst

Article abstract of DOI:10.1016/0040-4020(92)80014-7

(2S,3S,4S)-4-(Amino-2,3-epoxy-1-alkanol gave 4-amino-1,3-alkanediol or 3,4-imino-1,2-alkanediol with Dibal or Ti(O-i-Pr)4 respectively and, after introduction of Boc group to its amino group, afforded a 4-amino-1,2,3-alkanetriol derivative under the influ