A versatile approach to 2,3-disubstituted indoles through the palladium-catalysed cyclization of oalkynyltrifluoroacetanilides with vinyl triflates and aryl halides

DOI: 10.1016/S0040-4039(00)74818-0

Source and publish data:

Tetrahedron Letters p. 3915 - 3918 (1992)

Update date:2022-08-04

Topics: Cyclization Aryl Halides 2,3-Disubstituted Indoles Palladium-catalysed Vinyl Triflates

Authors:

Arcadi, Antonio

Cacchi, Sandro

Marinelli, Fabio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)74818-0

The palladium-catalysed cyclization of o-alkynyltrifluoroacetanilides with vinyl triflates and aryl halides produces 2,3-disubstituted indoles in good to high yield.

Full text of DOI:10.1016/S0040-4039(00)74818-0

Products guided by the article

Product name:(8R,9S,10R,13S,14S)-10,13-Dimethyl-3-(2-phenyl-1H-indol-3-yl)-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-cyclopenta[a]phenanthren-17-one

Cas No:143360-84-3

R&D Labs maybe for 143360-84-3

Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Jiangsu Wanlong Chemical Co., Ltd.

website:http://www.wanlongchem.com

Contact:+86-511-86810993 0086-511-8681 0888;

Address:Quanzhou Town, Danyang City, Jiangsu
KODI CHEMICAL CO., LTD

Contact:021

Address:Pudong
Eastar Chemical Corporation

website:http://www.eastarchem.com/

Contact:1-800-898-2436

Address:1215 K Street, STE 1700
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE

Relevant to this article

Copper(ii)-catalyzed coupling reaction: An efficient and regioselective approach to N′,N′-diaryl acylhydrazines

Doi:10.1039/c4ob02343a
(2015)
1-Phenyl-1-benzothiophenium Triflates by a Direct S-Phenylation with Diphenyliodonium Triflate

Doi:10.1246/bcsj.71.1215
(1998)
A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H₂O/TBAB

Doi:10.1016/j.tetlet.2019.06.047
(2019)
Preparation and reactions of enantiomerically pure α-functionalized grignard reagents

Doi:10.1021/ja4033956
(2013)
Radiosynthesis and evaluation of [¹¹C]EMPA as a potential PET tracer for orexin 2 receptors

Doi:10.1016/j.bmcl.2013.03.079
(2013)
Intramolecular 1,3-dipolar cycloaddition-mediated stereoselective synthesis of disubstituted cyclopentane: A simple model for the cyclopentane ring system of polycyclic oroidine alkaloids

Doi:10.1002/asia.201200820
(2013)

Article Doi