A versatile approach to 2,3-disubstituted indoles through the palladium-catalysed cyclization of oalkynyltrifluoroacetanilides with vinyl triflates and aryl halides

DOI: 10.1016/S0040-4039(00)74818-0

Source and publish data:

Tetrahedron Letters p. 3915 - 3918 (1992)

Update date:2022-08-04

Topics: Cyclization Aryl Halides 2,3-Disubstituted Indoles Palladium-catalysed Vinyl Triflates

Authors:

Arcadi, Antonio

Cacchi, Sandro

Marinelli, Fabio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)74818-0

The palladium-catalysed cyclization of o-alkynyltrifluoroacetanilides with vinyl triflates and aryl halides produces 2,3-disubstituted indoles in good to high yield.

Full text of DOI:10.1016/S0040-4039(00)74818-0

Products guided by the article

Product name:(8R,9S,10R,13S,14S)-10,13-Dimethyl-3-(2-phenyl-1H-indol-3-yl)-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-cyclopenta[a]phenanthren-17-one

Cas No:143360-84-3

R&D Labs maybe for 143360-84-3

ANTAI BIO-TECH CO LTD

website:http://www.antaibio.com

Contact:0086-21-65663057

Address:Room 2108, Building 2，No. 489 Zhengli Road，200433
Wuhan Kemi-Works Chemical Co., Ltd

website:http://www.kemiworks.com

Contact:86-27-85736489

Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Anhui Sholon New Material Technology Co., Ltd.

website:http://www.sholonchem.com

Contact:+86-550-5261666

Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province

Relevant to this article

Copper(ii)-catalyzed coupling reaction: An efficient and regioselective approach to N′,N′-diaryl acylhydrazines

Doi:10.1039/c4ob02343a
(2015)
1-Phenyl-1-benzothiophenium Triflates by a Direct S-Phenylation with Diphenyliodonium Triflate

Doi:10.1246/bcsj.71.1215
(1998)
A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H₂O/TBAB

Doi:10.1016/j.tetlet.2019.06.047
(2019)
Preparation and reactions of enantiomerically pure α-functionalized grignard reagents

Doi:10.1021/ja4033956
(2013)
Radiosynthesis and evaluation of [¹¹C]EMPA as a potential PET tracer for orexin 2 receptors

Doi:10.1016/j.bmcl.2013.03.079
(2013)
Intramolecular 1,3-dipolar cycloaddition-mediated stereoselective synthesis of disubstituted cyclopentane: A simple model for the cyclopentane ring system of polycyclic oroidine alkaloids

Doi:10.1002/asia.201200820
(2013)

Article Doi