Heterocycles p. 1295 - 1298 (1992)
Update date:2022-08-03
Topics:
Somei, Masanori
Kobayashi, Tetsuya
A regioselective lithiation of 1-methoxymethoxyindole at the 2-position was achieved with n-BuLi at 0 deg C.Subsequent treatment with electrophiles afforded 2-substituted 1-methoxymethoxyindoles, which were readily converted to 2-substituted indoles.
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