Synthetic Studies on Leinamycin. A Synthesis of the 1-Oxo-1,2-dithiolan-3-one Moiety

DOI: 10.1016/0040-4039(92)89010-A

Source and publish data:

Tetrahedron Letters p. 5701 - 5704 (1992)

Update date:2022-07-29

Topics:

Authors:

Kanda, Yutaka

Saito, Hiromitsu

Fukuyama, Tohru

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(92)89010-A

A synthesis of the 1-oxo-1,2-dithiolan-3-one moiety of antitumor antibiotic leinamycin (1) i described.An intramolecular delivery of a sulfur atom (7 to 8) and a facile Beckmann fragmentation (10 to 12) constitute the backbone of our synthesis.

Full text of DOI:10.1016/0040-4039(92)89010-A

Products guided by the article

Product name:(E)-3-Methyl-4-oxo-pent-2-enoic acid cyclohexylamide

Cas No:144536-39-0

R&D Labs maybe for 144536-39-0

Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China
Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd

Contact:86-27-52341789

Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Jiangsu Haian Petro chemical Plant

Contact:+86-513-88902723

Address:99, Changjiang West Road, Haian County, Jiangsu
Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Beyond Pharmaceutical Co., Ltd

Contact:+86-571-8195-3185

Address:No. 13-1, Liansheng Road, Yuhang District

Relevant to this article

A supramolecular DNA self-assembly based on β-cyclodextrin-adamantane complexation as a bioorthogonal sticky end motif

Doi:10.1039/c3cc43109f
(2013)
High-intensity near-IR fluorescence in semiconducting polymer dots achieved by cascade FRET strategy

Doi:10.1039/c3sc50222h
(2013)
Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids

Doi:10.1016/S0040-4039(00)61150-4
(1992)
Catalyzed Claisen rearrangements of O-allyl kojates

Doi:10.1016/j.tetlet.2013.05.002
(2013)
Calix[4]quinone. Part 2: Intramolecular Michael-addition of calix[4]diquinone

Doi:10.1016/S0040-4020(01)00788-8
(2001)
Optically pure, crystalline 'acetate'-aldols from Nacetylbornane-10,2-sultam

Doi:10.1016/S0040-4039(00)92209-3
(1992)

Article Doi