Tetrahedron Asymmetry p. 1213 - 1221 (1992)
Update date:2022-09-26
Topics: Synthesis Enantiomer Chirality Homochiral Racemic mixture Glutamic acid
Herdeis, C.
Hubmann, H. P.
A streoselective synthesis of R-Baclofen is presented starting from S-pyroglutamic acid derivative 3.The key steps are the 1,4-conjugate addition of Grignard cuprate (p-ClPh)2CuMgCl to 3 and Barton-Decarboxylation of 6e to 7e.
View MoreBeijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Shijiazhuang Sdyano Fine Chemical Co., Ltd
Contact:+86-311-89830448
Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Shijiazhuang Frontierchem Co., Ltd.
Contact:+86-311-89271196
Address:4-4-202 No.15 Biandian Street,Shijiazhuang
Shanghai Puda Chemical Co.,Ltd
Contact:+86+571+56565965
Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
Suzhou Lixin Pharmaceutical Co., Ltd.
Contact:86-512-88169812
Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Doi:10.1039/c3cc43216e
(2013)Doi:10.1016/S0020-1693(00)92368-5
(1992)Doi:10.1021/acs.joc.7b03198
(2018)Doi:10.1016/j.bmcl.2017.01.084
(2017)Doi:10.1016/S0020-1693(00)92345-4
(1992)Doi:10.1002/chem.201204364
(2013)
