
Australian Journal of Chemistry p. 1571 - 1576 (1992)
Update date:2022-07-30
Topics:
Donkor, Augustine
Prager, Rolf H.
Thompson, Malcolm J.
Reaction of diethyl ethoxymethylenemalonate with sodium azide in trifluoroacetic acid at 20 deg gives ethyl 5-ethoxyisoxazole-4-carboxylate (67percent), diethyl cyanomalonate (21percent) and diethyl ethoxyaminomethylenmalonate (5percent).The last compound and its tautomer are converted into ethyl 1-ethoxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate.The product structures have been confirmed by synthesis or degradation.
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Doi:10.1016/S0040-4039(00)60938-3
(1992)Doi:10.1039/c3tc30967c
(2013)Doi:10.1016/0040-4020(73)80173-5
(1973)Doi:10.1021/jo00053a049
(1993)Doi:10.1021/jo972168h
(1998)Doi:10.1016/S0040-4020(01)81194-7
(1992)