95. Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues

DOI: 10.1002/hlca.19970800421

Source and publish data:

Helvetica Chimica Acta p. 1244 - 1259 (1997)

Update date:2022-08-04

Topics:

Authors:

DeVita, Robert J.

Frontier, Alison J.

Schoen, William R.

Wyvratt, Matthew J.

Fisher, Michael H.

Cheng, Kang

Chan, Wanda W.-S.

Butler, Bridget S.

Smith, Roy G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/hlca.19970800421

The synthesis of a variety of potent macrocyclic growth hormone secretagogues, i.e. 5, 9, 12, and 20-22, based on the known lead structure L-692,429 (1) is described. These conformationally constrained growth hormone secretagogues were prepared by joining

Full text of DOI:10.1002/hlca.19970800421

Products guided by the article

Product name:4'-[(R)-3-(3-Amino-3-methyl-butyrylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-ylmethyl]-biphenyl-2-carboxylic acid tert-butyl ester

Cas No:145486-07-3

R&D Labs maybe for 145486-07-3

Beijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)

Contact:010-52876516

Address:tongzhoubeiyuan
Alway Chem, China

website:http://www.alwaychem.com

Contact:+86-532-8586-4000, 8586-5000

Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
Ring Specialty Chemicals Inc.

website:http://www.ringchemicals.com/

Contact:+1-416-493-6870

Address:Toronto, Canada
Jintan City Mego Chemical Co., Ltd

Contact:+86-0519-82814387

Address:23# Dengguan Town, Jintan, Jiangsu Province, China
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china

Relevant to this article

Tricyclic 'oxadiazoaphosphorine oxide' guanosines: A new strategy to the protection of guanine bases during RNA synthesis

Doi:10.1016/S0040-4039(00)61764-1
(1992)
Total synthesis of attenols A and B

Doi:10.1016/j.tetlet.2013.08.043
(2013)
Singlet oxygen in synthesis. Oxazoles as carbonyl 1,1-dipole synthons

Doi:10.1016/S0040-4039(00)60874-2
(1992)
Catecholamine-protein conjugates: Isolation of an adduct of N-acetylhistidine to the side chain of N-acetyldopamine from an insect-enzyme catalyzed reaction

Doi:10.1016/S0040-4039(00)92150-6
(1991)
Diversity-oriented synthesis of spiro-oxindole-based 2,5-dihydropyrroles via three-component cycloadditions and evaluation on their cytotoxicity

Doi:10.1039/c3ra40874d
(2013)
Doi:10.1016/S0008-6215(00)81111-8
(1967)

Article Doi