Synthesis and oligomerization of N(δ)-Boc-N(α)-(thymin-1-ylacetyl)ornithine

DOI: 10.1016/0960-894X(96)00121-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 793 - 796 (1996)

Update date:2022-08-03

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Authors:

Petersen

Buchardt

Nielsen Nielsen

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Article abstract of DOI:10.1016/0960-894X(96)00121-7

The synthesis of a new DNA analogue based on ornithine is described. Only the thymine analogue was synthesised. A 10 mer entirely made up of the thymine monomer forms a triple helix with poly RNA A. The T(m) of the triplex was 21°C.

Full text of DOI:10.1016/0960-894X(96)00121-7

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