Synthesis p. 1053 - 1054 (1992)
Update date:2022-08-03
Topics:
Martinez, A. Garcia
Fernandez, A. Herrera
Vilchez, Dolores Molero
Hanack, M.
Subramanian, L. R.
The reaction of alkyl and aryl α-halomethyl ketones 1 with aliphatic and aromatic nitriles 2 in the presence of trifluoromethanesulfonic anhydride affords substituted 5-halopyrimidines 3 in good yields (55-91percent).
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Doi:10.1016/S0008-6215(00)90925-X
(1992)Doi:10.1016/S0040-4039(00)60832-8
(1992)Doi:10.1080/00397919508011481
(1995)Doi:10.1039/DT9920003199
(1992)Doi:10.1055/s-1992-26344
(1992)Doi:10.1039/c3cc45413d
(2013)