Synthesis and evaluation of new 6-deoxy-6-fluorinated glucosides as inhibitors of yeast &α-glucosidase

DOI: 10.1016/S0022-1139(00)82408-2

Source and publish data:

Journal of Fluorine Chemistry p. 185 - 192 (1992)

Update date:2022-08-03

Topics:

Authors:

Halazy, Serge

Berges, Veronique

Ehrhard, Anne

Danzin, Charles

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Article abstract of DOI:10.1016/S0022-1139(00)82408-2

A series of 6-deoxy-6-fluorinated glucosides have been synthesized and evaluated as inhibitors of yeast α-glucosidase.These compounds have 7- to 25-fold higher affinity than the corresponding 6-hydroxy derivatives.The most potent inhibitor in the series w

Full text of DOI:10.1016/S0022-1139(00)82408-2

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