Efficient preparation of enol carbonates by selective O-acylation of ketone sodium enolates generated in the presence of TMEDA

Article abstract of DOI:10.1016/0040-4039(94)80040-5

Generating sodium enolates in the presence of TMEDA followed by inverse addition to chloroformate esters leads cleanly to the O-acylated materials and provides a practical means of preparing such derivatives. In the absence of TMEDA mixtures of O- and C-a