A Facile Synthesis of 2-exo-Methylenepenam; a Potent Intermediate for Syntheses of New β-Lactamase Inhibitors

DOI: 10.1039/c39920001793

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1793 - 1794 (1992)

Update date:2022-09-26

Topics:

Authors:

Tanaka, Hideo

Kameyama, Yutaka

Yamauchi, Takahito

Torii, Sigeru

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39920001793

A convenient synthesis of 2-exo-methylenepenams 1 is performed by reductive cyclization of allenecarboxylates 8 in a BiCl3/Zn bimetal redox system; subsequent manipulation of the 2-exo-methylene moiety of 1 opens new entries to β-lactam antibiotics and/or

Full text of DOI:10.1039/c39920001793

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:2-((R)-2-Benzenesulfonylsulfanyl-4-oxo-azetidin-1-yl)-buta-2,3-dienoic acid benzhydryl ester

Cas No:146383-35-9

R&D Labs maybe for 146383-35-9

HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
Nanjing Fubang Chemical Co.,Ltd

Contact:+86-25-83179199

Address:5F,Tianzheng international plaza,No399 Zhongyang Road ,Nanjing China
Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.

Contact:86-532-88250866

Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
HAINAN JINYING IMPORT AND EXPORT CO. LTD

Contact:+86-898-32875423

Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA

Relevant to this article

A bis(phosphine)-modified peptide ligand for stable and luminescent quantum dots in aqueous media

Doi:10.1055/s-0033-1339340
(2013)
REVISION OF THE STEREOCHEMISTRY IN TRICHODIOL, TRICHOTRIOL AND RELATED COMPOUNDS, AND CONCERNING THEIR ROLE IN THE BIOSYNTHESIS OF TRICHOTHECENE MYCOTOXINS

Doi:10.1016/0031-9422(92)80114-T
(1993)
Synthetic studies on the compounds related to neocarzinostatin chromophore. 3. Novel synthesis of a chiral cyclic dienediyne system

Doi:10.1016/S0040-4020(01)80546-9
(1993)
New synthetic approach to coumarino[4,3-b]pyridine systems and potential cytotoxic evaluation

Doi:10.1007/s00044-013-0859-y
(2014)
Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents

Doi:10.1021/acsmedchemlett.8b00125
(2018)
Reaction of HppE with substrate analogues: Evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement

Doi:10.1021/ja403441x
(2013)

Article Doi