Enzymatic Synthesis of 3-Hydroxybutyramides and their Conversion to Optically Active 1,3-Aminoalcohols

DOI: 10.1016/S0957-4166(00)86049-8

Source and publish data:

Tetrahedron Asymmetry p. 1519 - 1522 (1992)

Update date:2022-08-03

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Authors:

Garcia, Maria J.

Rebolledo, Francisca

Gotor, Vicente

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Article abstract of DOI:10.1016/S0957-4166(00)86049-8

3-Hydroxybutyramides are obtained in high optical yield from ethyl (+/-)-3-hydroxybutyrate and aliphatic amines when the reaction is catalyzed by Candida antarctica lipase.The chemical reduction of these 3-hydroxybutyramides yields the corresponding 1,3-a

Full text of DOI:10.1016/S0957-4166(00)86049-8

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